MTHFR and Detoxification in Lyme Disease

updated 6/26/20

Marty Ross MD on MTHFR & Lyme

In this video article, Marty Ross MD discusses MTHFR detoxification genetic defect in Lyme disease. Watch the video to learn: 

• what the MTHFR genetic defect is,
• how MTHFR defect can interfere with detoxification,
• why it is not always necessary to correct for this defect,
• how the gut microbiome can fix this problem even if you have a genetic defect,
• when to take supplements to correct this problem. 

After you watch the video, see how to treat MTHFR in the section located below the video.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Treatment of MTHFR Detoxification Defect

If a person has an MTHFR DNA mutation, also called a SNP,  and an elevated blood homocysteine level, consider treating for MTHFR defect using 5-MTHF and methylcobalamin combination. Once on a full dose of this add 5-MTHF.

• 5-MTHF 400 mcg and Methylcobalamin 400 mcg 1-3 pills 1 time a day. Start at 1 pill and increase every 7 days as tolerated up to 3 pills. Go slowly because opening up blocked detoxification with this supplement could cause more fatigue, body pain, and cognitive dysfunction.
• 5-MTHF 1 mg or 5-MTHF 5 mg 1 pill daily. Add the 1 mg dose after you are stable on the 5 MTHF/Methylcobalamin combination above. Only add the 5mg dose if advised by your physician.

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